Hubungan Daerah Tempat Tinggal dengan Gambaran Histopatologi Karsinoma Tiroid pada Masyarakat Sumatera Barat
DOI:
https://doi.org/10.25077/jka.v3i2.65Abstract
Abstrak
Karsinoma tiroid merupakan keganasan kelenjar endokrin yang paling sering ditemukan dan insidennya meningkat setiap tahun. Berdasarkan gambaran histopatologinya, karsinoma tiroid dibagi menjadi tipe papiler, folikuler, meduler, dan anaplastik. Salah satu faktor yang mempengaruhi gambaran histopatologi karsinoma tiroid adalah keadaan geografis, dimana karsinoma tipe folikuler dan anaplastik akan lebih sering ditemukan pada daerah beresiko defisiensi yodium dibandingkan daerah tidak beresiko defisiensi yodium. Tujuan dari penelitian ini adalah untuk mengetahui hubungan daerah tempat tinggal dengan gambaran histopatologi karsinoma tiroid. Penelitian ini menggunakan desain analitik observasional dengan mengumpulkan data sekunder di Laboratorium Patologi Anatomi FK Unand dan rekam medik RSUP M. Djamil periode Januari 2010 – Desember 2011 Dari penelitian ini ditemukan 102 kasus karsinoma tiroid, dimana 32 kasus bertempat tinggal di daerah beresiko defisiensi yodium dan 70 kasus bertempat tinggal di daerah tidak beresiko defisiensi yodium. Pada daerah beresiko defisiensi yodium, 34,4% merupakan karsinoma folikuler dan anaplastik, dan 65,5% merupakan karsinoma selain folikuler dan anaplastik. Pada daerah tidak beresiko defisiensi yodium, 22,9% merupakan karsinoma folikuler dan anaplastik, dan 77,1% merupakan karsinoma selain folikuler dan anaplastik. Dari analisis statistik hubungan daerah beresiko defisiensi yodium dengan kejadian karsinoma folikuler dan anaplastik berdasarkan uji chi-square didapatkan nilai p =0,33. Tidak terdapat hubungan bermakna antara daerah tempat tinggal dengan gambaran histopatologi karsinoma tiroid pada masyarakat Sumatera Barat pada periode Januari 2010 – Desember 2011. Kata kunci: Gambaran histopatologi karsinoma tiroid, daerah tempat tinggal
Kata kunci: Gambaran histopatologi karsinoma tiroid, daerah tempat tinggal
Abstract
Thyroid carcinoma is the most common endocrine tumor and is increasing in incidence every year. Based on histopathological types, thyroid carcinomas are divided into papillary carcinoma, follicular carcinoma, medullary carcinoma, and anaplastic carcinomas. Factors that can influence the histopathological type of thyroid carcinomas is geographical factor, which follicular and anaplastic type of thyroid carcinomas more frequently found in areas at risk of iodine deficiency than the area not at risk of iodine deficiency.The purpose of this study was to determine the relationship of residential areas with histopathologic types of thyroid carcinoma. This analytic research with observational design obtaining secondary data from Pathology Anatomy Laboratory of Medical Faculty of Andalas University and medical record of M. Djamil Hospital in a period of January 2010 – December 2011. From this reseach, found 102 cases of thyroid carcinoma, of which 32 cases residing in areas at risk of iodine deficiency and 70 cases residing in the area are not at risk of iodine deficiency. In areas at risk of iodine deficiency, 34.4% are follicular and anaplastic carcinomas, and 65.5% are papillary carcinomas. In areas not at risk of iodine deficiency, 22.9% are follicular and anaplastic carcinomas, and 77.1% are papillary carcinomas. Statistical analysis of the relationship of the area at risk of iodine deficiency with follicular and anaplastic carcinoma incidence by chi-square test p value = 0.32.There is no significant correlation between residential areas and histopathological types of thyroid carcinoma of West Sumatera society.
Keywords:Histopathological types of thyroid carcinoma, residential areas
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