Gambaran Profil Lipid Pasien Perlemakan Hati Non-Alkoholik

Vanny Syafitri, Arnelis Arnelis, Efrida Efrida

Abstract


Abstrak
Penyakit perlemakan hati non-alkoholik (non-alcoholic fatty liver disease) merupakan kondisi klinis yang sering ditemukan dalam bidang hepatologi. Salah satu faktor risiko penyakit ini adalah dislipidemia. Penelitian ini dilakukan untuk mengetahui distribusi frekuensi profil lipid pasien perlemakan hati non-alkoholik dengan dislipidemia. Penelitian dilakukan secara retrospektif di RS DR. M. Djamil Padang terhadap pasien perlemakan hati non-alkoholik dengan dislipidemia periode 2010–2013. Dari 118 pasien perlemakan hati non-alkoholik dengan dislipidemia hanya 43 subyek yang memenuhi kriteria penelitian. Rata-rata umur subjek penelitian pada laki-laki adalah 48,53±11,92 tahun dan perempuan 49,58±11,01 tahun. Subjek penelitian didominasi oleh perempuan dengan perbandingan 1,5:1 terhadap laki-laki. Didapatkan pasien hiperkolesterolemia sebanyak 61,82% , hipo-HDL-emia 86,05%, hiper-LDL-emia 44,19%, hipertrigliseridemia 55,81%. Kesimpulannya, pada perlemakan hati non-alkoholik ditemukan kadar kolesterol total dan trigliserida yang tinggi, kadar LDL yang normal serta kadar HDL yang rendah.
Kata kunci: Profil lipid, perlemakan hati non-alkoholik, dislipidemia

Abstract
Non-alcoholic fatty liver disease is a clinical condition that is often found in the field of hepatology. One of the risk factors for this disease is dyslipidemia. This study was conducted to determine distribution and frequency of the lipid profile patients non-alcoholic fatty liver with dyslipidemia.A retrospective study was conducted at DR. M. Djamil Padang hospital to patients of non-alcoholic fatty liver with dyslipidemia within 2010-2013. A total of 118 non-alcoholic fatty liver with dyslipidemia patients only 43 subjects who met the study criteria.The average age of the subjects were males 48.53±11.92 years and women 49.58±11.01 years. Subject is dominated by women against men with 1.5:1 ratio. This study observed that patient with hypercholesterolemia as much as 61.82%, hypo-HDL-emia 86.05%, hyper-LDL-emia 44.19%, hypertriglyceridemia 55.81%.It can be concluded patient of non-alcoholic fatty liver disease with dyslipidemia has high total cholesterol and triglyceride levels, normal LDL levels and low HDL levels
Keywords:Lipid profile, non-alcoholic fatty liver disease, dyslipidemia


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DOI: http://dx.doi.org/10.25077/jka.v4i1.234

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Copyright (c) 2015 Vanny Syafitri, Arnelis Arnelis, Efrida Efrida

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