Hubungan Jumlah Trombosit, Hematokrit dan Hemoglobin dengan Derajat Klinik Demam Berdarah Dengue pada Pasien Dewasa di RSUP. M. Djamil Padang
Abstract
Abstrak
Diagnosis yang tepat terhadap stadium dan kondisi penderita DBD penting untuk menentukan prognosisnya. Pemeriksaan trombosit, hematokrit, dan hemoglobin untuk setiap derajat klinik DBD diharapkan membantu dalam mengelompokkan dan mengelola pasien berdasarkan derajat kliniknya. Penelitan ini bertujuan untuk melihat hubungan hasil pemeriksaan trombosit, hematokrit, dan hemoglobin dengan derajat klinik DBD berdasarkan kriteria WHO.Penelitian dilakukan secara retrospektif terhadap 84 sampel dari rekam medik Bagian Ilmu Penyakit Dalam di RSUP. M. Djamil Padang dari januari 2011 sampai 30 April 2013. Trombosit diperiksaan menggunakan metode Rees Ecker, hematokrit dengan metode langsung cara mikro, dan hemoglobin menggunakan metode Sahli. Uji hipotesis menggunakan analisis bivariat dengan uji hipotesis nonparametrik Kendal’s Tau dengan software SPSS.Hasil penelitian ditemukan rerata umur 25.49±10.09 tahun. Laki-laki 46 orang (54.8%) lebih banyak dari wanita 38 orang (45.2%). Hasil analisis dengan uji korelasi Kendal’s Tau didapatkan trombosit berhubungan dengan derajat klinik DBD, semakin rendah trombosit semakin berat derajat kliniknya (p < 0.05, r = 0.336). Hematokrit tidak berhubungan dengan derajat klinik DBD (p > 0.05, r = 0.059). Hemoglobin tidak berhubungan dengan derajat klinik DBD (p > 0.05, r = - 0.036).Semakin rendah jumlah trombosit semakin berat derajat klinik DBD, hematokrit dan hemoglobin tidak berhubungan dengan derajat klinik DBD.
Kata kunci: jumlah trombosit, nilai hematokrit, kadar hemoglobin, derajat klinik DBD.
Abstract
Prompt diagnosis and as an accurate assessment of the stage and condition of DHF cases is a very important factor for determining patient prognosis. The existence of an exact value of the results of platelets, hematocrit, and hemoglobin for each grade of DHF are expected to greatly assist in classify and manage patients based on the clinical degree. This research was aimed to determine the relationship between the results of the hemoglobin, hematocrit and platelets count with the degree of clinical DHF according to WHO criteria. This research with retrospective design in 84 samples were taken from the medical records of adult patients in RSUP. M. Djamil Padang from 1 January 2011 until 30 April 2013. Platelets used direct method Rees Ecker, hematocrit’s used direct method micro method, and hemoglobin’s used Sahli method. Data processed by Kendal Tau tests using SPSS software. Results found average ages of 25.49 ± 10,09 years. The number of male patients 46 (54.8%) higher than female patients 38 (45.2%). Analysis by hypotetic test showed that there is a relationship between the platelet with clinical degree of DHF, where the lower the number, the more severe the clinical degree of DHF (p < 0.05, r = - 0336). There is no relation between hematocrit with clinical degree of DHF (p > 0.05, r = 0.059). There is no relation between hemoglobin with clinical degree of DHF (p > 0.05, r = - 0.036). More lower the number of trombosit, the more severe the clinical degree of DHF, and there is no relation between hematocrit and hemoglobin with clinical degree of DHF.
Keywords: platelet count, hematocrit, hemoglobin levels, clinical degree of DHF.
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PDFDOI: http://dx.doi.org/10.25077/jka.v3i3.187
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