Pola Sensitivitas Bakteri Penyebab Infeksi Saluran Napas Bawah Non Tuberkulosis Terhadap Kotrimoksazol di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode 1 Januari 2012 – 31 Desember 2012

Inez Amelinda, Aziz Djamal, Elly Usman

Abstract

Abstrak
Penyakit infeksi saluran napas, terutama Infeksi Saluran Napas Bagian Bawah (ISPB) non tuberkulosis merupakan masalah kesehatan yang sering dihadapi. Penegakan diagnosis secara tepat dan tepat serta pemilihan antibiotika berdasarkan uji sensitivitas akan sangat membantu dalam tatalaksana penyakit. Kotrimoksazol merupakan antibiotika lini pertama dan banyak digunakan dibeberapa puskesmas sebagai salah satu pengobatan infeksi saluran napas bawah non tuberkulosis.Tujuannya untuk mengetahui bakteri penyebab infeksi saluran napas bawah serta sensitivitasnya terhadap kotrimoksazol. Penelitian ini merupakan studi deskriptif yang bersifat cross-sectional. Hasil penelitian menunjukkan bahwa terdapat 671 permintaan pemeriksaan mikrobiologis yang mencantumkan diagnosis klinis sebagai infeksi saluran napas bawah non tuberkulosis, sebagian besar ditegakkan diagnosis pneumonia (87,78%), diikuti oleh bronkiektasis (5,96%), bronkitis kronis (4,32%), dan bronkitis akut (1,94%). Selain itu, dari hasil penelitian ditemukan bakteri penyebab terbanyak infeksi saluran napas bawah non tuberkulosis yang utama adalah Klebsiella pneumoniae (51,92%), Streptococcus α hemolyticus (17,78%), dan Pseudomonas sp. (9,25%). Persentase sensitivitas bakteri penyebab infeksi saluran napas bawah terhadap kotrimoksazol sebesar 18,78%.
Kata kunci: infeksi saluran napas bawah non tuberkulosis, bakteri penyebab, sensitivitas, kotrimoksazol

Abstract
Respiratory tract infections diseases, especially lower respiratory tract infections non tuberculosis is a health problem that is often encountered. Proper diagnosis and appropriate antibiotic selection based on testing and sensitivity will be helpful in the treatment of disease. Co-trimoxazole is a first-line antibiotic and widely used in several health centers as one of the treatment of lower respiratory tract infections non tuberculosis.The goal of this research was to discover which bacterium causes lower respiratory tract infection and its sensitivity to Cotrimoxazole. This research was a cross-sectional descriptive study. The results of research showed that there were 671 requests for microbiological examination which included a clinical diagnosis of lower respiratory tract infectionas non-tuberculosis, most revealed clinical sign as pneumonia (87,78%), followed by bronchiectasis (5,96%), chronicbronchitis (4,32%), and acutebronchitis (1,94%). Besides that, according to the research result, bacteria that cause lower respiratory tract infection are Klebsiella pneumoniae (51,92%), Streptococcus α hemolyticus (17,78%), and Pseudomonas sp. (9,25%). All the bacteria has 18,78% sensitivity to cotrimoxazole.
Keywords:lower respiratory tract infection, bacteria, sensitivity, cotrimoxazole.

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