Kelainan Hemostasis pada Leukemia

Authors

  • Zelly Dia Rofinda

DOI:

https://doi.org/10.25077/jka.v1i2.40

Abstract

Abstrak
Latar belakang: Leukemia adalah penyakit keganasan pada jaringan hematopoietik yang ditandai dengan
penggantian elemen sumsum tulang normal oleh sel darah abnormal atau sel leukemik. Salah satu manifestasi klinis
dari leukemia adalah perdarahan yang disebabkan oleh berbagai kelainan hemostasis.
Kelainan hemostasis yang dapat terjadi pada leukemia berupa trombositopenia, disfungsi trombosit,
koagulasi intravaskuler diseminata, defek protein koagulasi, fibrinolisis primer dan trombosis. Patogenesis dan
patofosiologi kelainan hemostasis pada leukemia tersebut terjadi dengan berbagai mekanisme.
Kata kunci: leukemia, kelainan hemostasis
Abstract
Background: AbstractLeukemia is a malignancy of hematopoietic tissue which is characterized by
substituted of bone marrow element with abnormal blood cell or leukemic cell. One of clinical manifestation of
leukemia is bleeding that is caused by several hemostasis disorders.Hemostasis disorders in leukemia such as
thrombocytopenia, platelet dysfunction, disseminated intravascular coagulation, coagulation protein defect, primary
fibrinolysis and thrombosis. Pathogenesis and pathophysiology of thus hemostasis disorders in leukemia occur with
different mechanism.
Keywords: leukemia, hemostasis disorder

Downloads

Published

2012-09-01

How to Cite

Dia Rofinda, Z. (2012). Kelainan Hemostasis pada Leukemia. Jurnal Kesehatan Andalas, 1(2). https://doi.org/10.25077/jka.v1i2.40

Issue

Vol. 1 No. 2 (2012)

Section

Literature Review

License

Authors retain copyright and grant the Jurnal Kesehatan Andalas right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike (CC BY-SA 4.0) license that allows others to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material) the work for any purpose, even commercially with an acknowledgement of the work's authorship and initial publication in Jurnal Kesehatan Andalas.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in Jurnal Kesehatan Andalas.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).