Korelasi Skor SOFA dengan Kadar Kortisol Darah pada Pasien Sepsis di RSUP Dr. M. Djamil Padang

Authors

  • Rahmadina Zesfira Fahmi Program Studi Kedokteran, Fakultas Kedokteran, Universitas Andalas
  • Fadrian Fadrian Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran, Universitas Andalas
  • Rikarni Rikarni Departemen Patologi Klinik, Fakultas Kedokteran, Universitas Andalas
  • Husni Husni Departemen Patologi Klinik, Fakultas Kedokteran, Universitas Andalas
  • Rohayat Bilmahdi Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran, Universitas Andalas
  • Miftah Irramah Departemen Fisiologi, Fakultas Kedokteran, Universitas Andalas

DOI:

https://doi.org/10.25077/jka.v14i3.2671

Abstract

Sepsis is a life-threatening organ dysfunction due to dysregulation of the body's immune response to infection. The Sequential Organ Failure Assessment score (SOFA score) is a diagnostic tool used to quantitatively and objectively assess the level of organ dysfunction. Sepsis as a stressor of systemic inflammation, causes an increase in cortisol secretion by the adrenals to target tissues, which suppresses inflammation. Objective: To determine the correlation between SOFA score and blood cortisol levels in sepsis patients at RSUP Dr. M. Djamil Padang. Method: Observational analytic study with a cross-sectional method. The sample consisted of 55 patients who had been diagnosed with sepsis. The data used was secondary data from medical records. The data were tested using the Spearman correlation test. Result: A correlation was found between the SOFA score and blood cortisol levels, yielding a correlation coefficient of r = 0.338 and a p-value of 0.012. Conclusion: There is a significant moderate correlation between SOFA scores and blood cortisol levels.

Keywords:  blood cortisol, sepsis, SOFA score

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Published

2025-12-27

How to Cite

Fahmi, R. Z., Fadrian, F., Rikarni, R., Husni, H., Bilmahdi, R., & Irramah, M. (2025). Korelasi Skor SOFA dengan Kadar Kortisol Darah pada Pasien Sepsis di RSUP Dr. M. Djamil Padang. Jurnal Kesehatan Andalas, 14(3), 60–66. https://doi.org/10.25077/jka.v14i3.2671

Issue

Vol. 14 No. 3 (2025): November 2025

Section

Research Articles

License

Copyright (c) 2025 Rahmadina Zesfira Fahmi, Fadrian Fadrian, Rikarni Rikarni, Husni Husni, Rohayat Bilmahdi, Miftah Irramah

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