Talaromycosis Marneffei pada Pasien HIV
DOI:
https://doi.org/10.25077/jka.v9i3.1331Abstract
Talaromycosis marneffei adalah infeksi jamur yang disebabkan Talaromyces marneffei. Talaromikosis adalah salah satu infeksi oportunistik yang sering mengenai orang dengan infeksi Human Immunodeficiency Virus (HIV) stadium akhir di Asia Tenggara, India timur laut, Cina Selatan, Hongkong, dan Taiwan. Gejala klinis talaromikosis tidak spesifik, seperti demam, anemia, penurunan berat badan, hepatomegali, splenomegali, gangguan pernapasan dan manifestasi kulit. Diagnosis ditegakkan berdasarkan kecurigaan klinis dengan konfirmasi pemeriksaan histopatologi. Dilaporkan pasien laki-laki berusia 29 tahun, dirawat di Bagian Penyakit Dalam RSUP Dr. M. Djamil Padang, dengan keluhan utama muncul bintil-bintil berwarna kehitaman hampir diseluruh wajah sejak 3 bulan yang lalu. Pasien sudah dikenal menderita HIV sejak 4 bulan yang lalu dan sudah mendapat terapi antiretroviral (ARV). Didapatkan plak hiperpigmentasi pada wajah dan hepatomegali. Laboratorium didapatkan kadar hemoglobin 8,9 gr/dl, CD4 8 sel/uL dan pemeriksaan histopatologi yang menunjukkan massa sporis eosinofilik di intraseluler dan diantara stroma jaringan ikat. Pemberian ARV dilanjutkan dan juga diberikan antijamur.
Kata kunci: human immunodeficiency virus, talaromycosis, talaromyces marneffei
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- 2025-03-24 (2)
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