Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue

Authors

  • Ayu Safitri Sholihah Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram
  • I Gusti Ayu Nyoman Danuyanti Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram
  • Siti Zaetun Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram
  • Pancawati Ariami Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram
  • Ersandhi Resnhaleksmana Teknologi Laboratorium Medis, Poltekkes Kemenkes Mataram

DOI:

https://doi.org/10.25077/jka.v11i2.2032

Abstract

Dengue Hemorrhagic Fever diagnosis is supported by examining Blue Plasma Lymphocytes and C-Reactive Protein, in which Blue Plasma Lymphocytes can distinguish Dengue and Non-Dengue infections. At the same time, the C-Reactive Proteins are used to see the presence of inflammation due to infections such as Dengue Virus infection. Objectives: To analyzed the correlation of the number of Blue Plasma Lymphocytes with C-Reactive Protein (CRP) levels in Dengue Hemorrhagic Fever patients. Methods: This study was analytical observational research with a cross-sectional design. The sample used was a patient diagnosed with DHF with a positive Nonstructural protein 1 (NS1) or Rapid Diagnostic Test (RDT) IgG/IgM result. The data was collected and analyzed using Spearman's rank statistical test. Results: The average number of Blue Plasma Lymphocytes in positive samples was 8%, with the number of negative results, namely 4 (13.33%) samples and 26 (86.67%) samples with positive Blue Plasma Lymphocyte results. The average level of C–Reactive Protein in the positive samples was 29.36 mg/L, with results that had normal levels were 11 (36.67%) samples and 19 (63.33%) samples with abnormal C-Reactive Protein levels. Spearman's Rank statistical test results obtained a value of p = 0.000 < 0.05, indicating a correlation between the number of Blue Plasma Lymphocytes and C–Reactive  Protein levels in Dengue Hemorrhagic Fever patients. Conclusion: The more Blue Plasma Lymphocytes, the higher C–Reactive Protein levels in Dengue Hemorrhagic Fever.

Keywords: blue plasma lymphocytes, C–reactive protein, dengue hemorrhagic fever

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Published

2022-12-26 — Updated on 2025-03-20

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How to Cite

Sholihah, A. S., Danuyanti, I. G. A. N., Zaetun, S., Ariami, P., & Resnhaleksmana, E. (2025). Korelasi Temuan Limfosit Plasma Biru dengan Kadar C-Reaktif Protein sebagai Penunjang dalam Diagnosis Demam Berdarah Dengue. Jurnal Kesehatan Andalas, 11(2), 111–117. https://doi.org/10.25077/jka.v11i2.2032 (Original work published December 26, 2022)

Issue

Vol. 11 No. 2 (2022): Online July 2022

Section

Research Articles

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Copyright (c) 2022 Ayu Safitri Sholihah, I Gusti Ayu Nyoman Danuyanti, Siti Zaetun, Pancawati Ariami, Ersandhi Resnhaleksmana

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