Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember

Authors

  • Sofia Yusnur Rafida Fakultas Kedokteran, Universitas Jember
  • Hairrudin Hairrudin Fakultas Kedokteran, Universitas Jember https://orcid.org/0000-0002-1628-5376
  • Muhammad Hasan Fakultas Kedokteran, Universitas Jember

DOI:

https://doi.org/10.25077/jka.v11i2.1999

Abstract

The neutrophil-to-lymphocyte ratio (NLR) and Procalcitonin (PCT) are biomarkers that represent inflammatory activity and immune status as predictors for the prognosis of COVID-19 patients. NLR values and PCT levels are positively correlated with the severity of COVID-19, but the relationship between the two biomarkers is unclear. Objectives: To analyzed the correlation between NLR values and PCT levels in COVID-19 patients in Jember Regency. Methods: This cross-sectional analytic observational study, conducted from March to April 2022, took data from 444 confirmed COVID-19 patients at the Jember Clinic Plantation Hospital. Secondary data were obtained from medical records of inpatients for the period January–December 2021. Results: The average NLR value was 8.58, while the average PCT level was 0.43 ng/mL. The results of the Spearman Correlation Analysis showed a positive correlation between NLR values and PCT levels in COVID-19 patients in the Jember Regency with a p-value = 0.00 and a moderate degree of correlation with an r count of 0.41. Conclusion: There is a positive correlation between NLR values and PCT levels for COVID-19 patients in Jember Regency. It is necessary to carry out routine NLR and PCT examinations to consider predictors of disease severity and prognosis in COVID-19 patients.

Keywords:  COVID-19, NLR, PCT

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Published

2022-12-26 — Updated on 2025-03-20

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How to Cite

Rafida, S. Y., Hairrudin, H., & Hasan, M. (2025). Hubungan Antara Nilai Neutrophil-to-Lymphocyte Ratio (NLR) dengan Kadar Procalcitonin (PCT) pada Pasien COVID-19 di Kabupaten Jember. Jurnal Kesehatan Andalas, 11(2), 87–94. https://doi.org/10.25077/jka.v11i2.1999 (Original work published December 26, 2022)

Issue

Vol. 11 No. 2 (2022): Online July 2022

Section

Research Articles

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Copyright (c) 2022 Hairrudin, Muhammad Hasan, Sofia Yusnur Rafida

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